Faculty resistance to Writing Across the Curriculum (WAC) is an issue that has been recognized by WAC program directors and practitioners for decades, yet it remains unresolved. Perhaps the problem is not resistance per se, but how we interpret and react to it. Faculty resistance is typically viewed as an impediment to the pedagogical change WAC programs hope to achieve. Moreover, the label of "resistance" is often used without further examination of the underlying causes. Based on research and experience as (...) doctoral Writing Fellows in the Borough of Manhattan Community College WAC Program, we argue that so-called resistances are often justified concerns in regard to implementing WAC under given institutional, disciplinary, departmental, and personal constraints. We also suggest that if we listen and respond to these concerns, they become means to facilitate faculty engagement with WAC. By working through their concerns and adapting WAC to their context, faculty can take ownership of WAC and further develop the practice. Thus, what at first appears to be an impediment to deep-rooted pedagogical change ”resistance” can be used to encourage faculty to make WAC their own. (shrink)

Representing species-specific proteins and protein complexes in ontologies that are both human and machine-readable facilitates the retrieval, analysis, and interpretation of genome-scale data sets. Although existing protin-centric informatics resources provide the biomedical research community with well-curated compendia of protein sequence and structure, these resources lack formal ontological representations of the relationships among the proteins themselves. The Protein Ontology (PRO) Consortium is filling this informatics resource gap by developing ontological representations and relationships among proteins and their variants and modified forms. Because (...) proteins are often functional only as members of stable protein complexes, the PRO Consortium, in collaboration with existing protein and pathway databases, has launched a new initiative to implement logical and consistent representation of protein complexes. We describe here how the PRO Consortium is meeting the challenge of representing species-specific protein complexes, how protein complex representation in PRO supports annotation of protein complexes and comparative biology, and how PRO is being integrated into existing community bioinformatics resources. The PRO resource is accessible at http://pir.georgetown.edu/pro/. (shrink)

The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein (...) research. PRO (http://pir.georgetown.edu/pro) is part of the Open Biomedical Ontologies (OBO) Foundry. (shrink)

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to (...) UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments. (shrink)

The Protein Ontology (PRO) web resource provides an integrative framework for protein-centric exploration and enables specific and precise annotation of proteins and protein complexes based on PRO. Functionalities include: browsing, searching and retrieving, terms, displaying selected terms in OBO or OWL format, and supporting URIs. In addition, the PRO website offers multiple ways for the user to request, submit, or modify terms and/or annotation. We will demonstrate the use of these tools for protein research and annotation.

Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

The Protein Ontology (PRO; http://purl.obolibrary.org/obo/pr) formally defines and describes taxon-specific and taxon-neutral protein-related entities in three major areas: proteins related by evolution; proteins produced from a given gene; and protein-containing complexes. PRO thus serves as a tool for referencing protein entities at any level of specificity. To enhance this ability, and to facilitate the comparison of such entities described in different resources, we developed a standardized representation of proteoforms using UniProtKB as a sequence reference and PSI-MOD as a post-translational modification (...) reference. We illustrate its use in facilitating an alignment between PRO and Reactome protein entities. We also address issues of scalability, describing our first steps into the use of text mining to identify protein-related entities, the large-scale import of proteoform information from expert curated resources, and our ability to dynamically generate PRO terms. Web views for individual terms are now more informative about closely-related terms, including for example an interactive multiple sequence alignment. Finally, we describe recent improvement in semantic utility, with PRO now represented in OWL and as a SPARQL endpoint. These developments will further support the anticipated growth of PRO and facilitate discoverability of and allow aggregation of data relating to protein entities. (shrink)

The debate concerning abortion abounds in miraculous narratives. Judith Jarvis Thomson has contrived the most celebrated set among related ones, to wit the “violinist analogy,” the “Good Samaritan” narrative, and the “Henry Fonda” allegory, by virtue of which, she intends, on the one hand, to argue that women’s right to autonomy outweighs the alleged fetus’s right to life, and on the other, to prove that no positive moral duties can be derived towards other persons alone from the fact that (...) a moral agent is ascribed certain rights. What this short paper endeavors to prove is that Thomson’s argumentation by analogy is a weak one, since neither the number nor the relevance of similarities invoked is adequate or satisfactory, while crucial parameters concerning the morality of abortion are being totally overlooked. (shrink)

L’œuvre de Judith Butler, largement reconnue pour son apport en études de genre, recèle d’ouvertures nombreuses sur l’animalité et à son rôle dans la constitution de l’humain. Construite en patchwork et sans prétention à la systématicité théorique, elle repose, dans des contextes toujours différents, la problématique de la régulation normative de la vie et de la mort. Aussi, c’est en prenant au sérieux la marge constituante qu’y représente la question animale et par la (re)lecture de ses textes consacrés à (...) l’étude de pratiques esthétiques et artistiques, que cet article propose un décentrement théorique pour penser la question politique des corps qui comptent des animaux. Il étudie, de manière comparée, les happenings publics de L214, 269Life, 269 Libération Animale et Anonymous for the Voiceless. Il suggère que les choix esthétiques de ces différents collectifs reflètent et alimentent un certain regard politique porté sur la cause animale et sa finalité aussi bien que sur le genre de subjectivité politique attribuée ou non aux animaux non-humains. Il montre d’abord que les animaux constituent, chez Judith Butler, d’autres corps qui comptent : il s’agit alors d’introduire la diversité des outils théoriques de læ philosophe qui articulent la dimension publique, esthétique et souvent même artistique de la vie des corps avec la question du politique. C’est cette fondation qui lui permet, ensuite, de s’atteler à l’élaboration d’une cartographie des articulations esthético-politiques dans les performances militantes antispécistes. Y sont discutées une esthétique humanimale subversive et critique du binarisme humain/animal, une esthétique de l’« horreur morale » qui appelle au changement de comportement individuel par la mise en évidence de la violence, et une esthétique de la reconnaissance, qui valorise la possibilité d’une égalité radicale entre humains et non-humains dans le partage de la précarité de toute vie et du deuil public de chaque mort. (shrink)

La précarité fait référence à l'existence de la rareté. Judith Butler montre l'impossibilité d'être un à travers le concept hégélien du sujet heureux. Le sujet ainsi défini est projeté sur l'Autre – langage, normes sociales, regard extérieur –, ce qui conduit à un état de vulnérabilité : je dépends de ce que je ne serai pas. Cependant, l'impuissance, loin d'être parfaite, peut se transformer en puissance sans s'affranchir des frontières qui la définissent, si elle défie les illusions modernes de (...) la sensualité et permet la présence et l'origine de la coexistence. De même, loin d'être la fin de l'éthique, celle-ci est différente pour chaque acteur du monde dans lequel il vit. (shrink)

이것은 행동에 유전자/환경 상호 작용의 훌륭한 검토 이며, 조금 일자 임에도 불구 하 고, 쉽고 가치 있는 읽기. 그(것)들은 행동에 유전학의 압도적인 충격을 보여주는 쌍둥이 연구 결과로 시작합니다. 그들은 공유 가정 환경이 행동에 거의 영향을 미치지 않으며 입양 된 자녀가 무작위로 선택된 사람들처럼 의붓 형제 자매와 다르게 자라는 사실을 확장하고 요약하는 주디스 해리스 (Judith Harris)의 점점 더 잘 알려진 연구에 주목합니다. 그들 (그리고 행동 유전학을 토론하는 거의 모든 사람들이) 주의하지 못하는 한 가지 기본 포인트는 우리의 성격의 모든 기초를 포함하여 (...) 인간의 행동 보편적 인 수백 (수천)이 정상의 변화가없는 유전자에 의해 100 % 결정된다는 것입니다. 모든 사람은 나무를 돌이 아닌 나무로 보고, 음식을 찾고 먹고, 화가 나고 질투합니다. 그래서, 그들은 주로 여기에 대해 이야기하는 것은 얼마나 많은 환경 (문화)가 자신의 외모보다는 다양한 특성이 표시되는 정도에 영향을 미칠 수 있습니다. 마지막으로, 그들은 우리와 모든 유기체가 자연의 우생학의 산물이며 의학, 농업 및 문명 전체와 자연 선택을 물리 치려는 시도가 이 일을계속하는 모든 사회에 재앙이라는 것을 주목하지 못하고, 일반적인 정치적으로 올바른 방식으로 우생학에 대해논의합니다. 모든 개념의 50%, 또는 약 1억 년 동안, 어머니가 인식하지 못하고 거의 모든 조기 자발적 낙태로 끝납니다. 결함이 있는 유전자의 이 자연적인 컬링은 진화를 유도하고, 상대적으로 유전적으로 건전하게 유지하고, 사회를 가능하게 합니다. 이형성은 문명을 파괴하기에 충분하지만 인구 과잉은먼저그것을 o것입니다. 현대 의 두 시스템 보기에서인간의 행동에 대한 포괄적 인 최신 프레임 워크를 원하는 사람들은 내 책을 참조 할 수 있습니다'철학의 논리적 구조, 심리학, 민d와 루드비히 비트겐슈타인과 존 Searle의 언어' 그리고 언어 2nd ed (2019). 내 글의 더 많은 관심있는 사람들은 '이야기 원숭이를 볼 수 있습니다 -철학, 심리학, 과학, 운명 행성에 종교와 정치 - 기사 및 리뷰 2006-2017' 3rd ed (2019) 및 기타. (shrink)

"On First Looking into Chapman's Homer" by John Keats, may seem archaic now, especially its language. But it expresses the poet's delight and excitement when he discovers a new literary revelation, hitherto hidden from him. He makes an intellectual discovery. I've had this sense of discovery when reading philosophy. Some new approach, some new idea, has made me see a concept I thought I understood in a different and more rigorous way; made me re- examine what I thought I'd (...) understood perfectly well before. It's not so much that the authors I was reading offered the last word on the subject, more that they offered the first word. Here are four examples. (shrink)

Il s’agit d’un excellent examen des interactions génétiques / environnement sur le comportement et, en dépit d’être un peu daté, est une lecture facile et utile. Ils commencent par des études jumelles qui montrent l’impact écrasant de la génétique sur le comportement. Ils notent les études de plus en plus connues de Judith Harris qui étendent et résument les faits que l’environnement familial partagé n’a presque aucun effet sur le comportement et que les enfants adoptés grandissent pour être aussi (...) différents de leurs demi-frères et soeurs que les personnes choisies au hasard. Un point fondamental qu’ils (et presque tous ceux qui discutent de la génétique comportementale) ne parviennent pas à noter est que les centaines (des milliers selon votre point de vue) des universels comportementaux humains, y compris toutes les bases de nos personnalités, sont 100% déterminés par nos gènes, sans aucune variation dans les normales. Tout le monde voit un arbre comme un arbre et non une pierre, cherche et mange de la nourriture, se met en colère et jaloux, etc. Donc, ce dont ils parlent surtout ici, c’est de la quantité d’environnement (culture) qui peut influer sur la mesure dans laquelle les divers traits sont montrés, plutôt que leur apparence. Enfin, ils discutent de l’eugénisme de la manière politiquement correcte habituelle, à défaut de noter que nous et tous les organismes sommes les produits de l’eugénisme de la nature et que les tentatives de vaincre la sélection naturelle avec la médecine, l’agriculture, et la civilisation dans son ensemble, sont désastreuses pour toute société qui persiste à le faire. Jusqu’à 50% de toutes les conceptions, soit environ 100 millions par an, se terminent par un avortement spontané précoce, presque tous sans que la mère soit au courant. Cet abattage naturel de gènes défectueux stimule l’évolution, nous maintient relativement génétiquement sains et rend la société possible. Dysgenics est suffisant pour détruire la civilisation, mais la surpopulation sera do ild’abord. Ceux qui souhaitent un cadre complet à jour pour le comportement humain de la vue moderne de deuxemssyst peuvent consulter mon livre 'The Logical Structure of Philosophy, Psychology, Mind and Language in Ludwig Wittgenstein et John Searle' 2nd ed (2019). Ceux qui s’intéressent à plus de mes écrits peuvent voir «Talking Monkeys --Philosophie, Psychologie, Science, Religion et Politique sur une planète condamnée --Articles et revues 2006-2017' 3rd ed (2019) et autres. (shrink)

The UNBELIEVABLE similar ideas between Theise and Menas’ ideas (2016) and my ideas (2002-2008) in Physics and Cognitive Neuroscience and Philosophy (the mind-brain problem, quantum mechanics, etc.) -/- (2016) Theise D. Neil (Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) and Kafatos C. Menas (bDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; cSchmid College of Science & Technology, Chapman University, Orange, CA, USA) (2016), REVIEW - Fundamental awareness: (...) A framework for integrating science, philosophy and metaphysics, in COMMUNICATIVE & INTEGRATIVE BIOLOGY, 2016, VOL. 9, NO. 3, e1155010 (19 pages), http://dx.doi.org/10.1080/19420889.2016.1155010 -/- A friend of mine indicated me the strike similarities between Theise and Kafatos’ ideas in their book (Fundamental awareness: A framework for integrating science, philosophy and metaphysics) and my ideas in 2002-20008! I do not have access to this book, but I investigate the ideas that are in a review about this work. Let me introduce the abstract of that Review: -/- The ontologic framework of Fundamental Awareness proposed here assumes that non-dual Awareness is foundational to the universe, not arising from the interactions or structures of higher level phenomena. The framework allows comparison and integration of views from the three investigative domains concerned with understanding the nature of consciousness: science, philosophy, and metaphysics. In this framework, Awareness is the underlying reality, not reducible to anything else. Awareness and existence are the same. As such, the universe is non-material, self-organizing throughout, a holarchy of complementary, process driven, recursive interactions. The universe is both its own first observer and subject. Considering the world to be non-material and comprised, a priori, of Awareness is to privilege information over materiality, action over agency and to understand that qualia are not a “hard problem,” but the foundational elements of all existence. These views fully reflect main stream Western philosophical traditions, insights from culturally diverse contemplative and mystical traditions, and are in keeping with current scientific thinking, expressible mathematically. (shrink)

Il s’agit ici de présenter une version raffinée du libéralisme de la peur de Judith Shklar : le libéralisme de la prudence. Après en avoir brièvement présenté les grandes lignes et les principales faiblesses, j’esquisse les contours du libéralisme de la prudence et montre comment il réalise, mieux que libéralisme de la peur, le programme minimaliste poursuivi par Shklar. Je montre ensuite comment le libéralisme de la prudence nous permet de sortir du dilemme libéral posé par la tradition postrawlsienne (...) : justifier le libéralisme sur des bases morales, au risque de le priver de neutralité, ou le justifier sur des bases réalistes hobbesiennes, au risque d’en faire l’otage des rapports de force changeants. Enfin, j’examine comme le principal défaut apparent du libéralisme de la prudence – à savoir son ascétisme programmatique – est en fait son principal mérite. (shrink)

FISIOLOGIA DA REPRODUÇÃO BOVINA: 2 - ESTRO E SERVIÇO -/- -/- INTRODUÇÃO -/- -/- A identificação de vacas em cio (estro ou cio) é, sem dúvida, a prática mais importante no manejo da reprodução do rebanho leiteiro. Apesar dos avanços no conhecimento da fisiologia da reprodução a nível celular e molecular, a identificação de vacas em estro continua sendo o problema reprodutivo mais importante e o que mais causa prejuízos econômicos. Na indústria de laticínios no Brasil, seu impacto não foi (...) estimado, porém, a estimativa feita por países como os Estados Unidos onde se perdem 300 milhões de dólares por ano pode dar uma ideia, atribuída apenas à baixa eficiência na detecção de estros. Por que é cada vez mais difícil detectar vacas em estro? A resposta está relacionada aos aspectos intrínsecos da vaca leiteira moderna, associadas as práticas de manejo dos rebanhos atuais, caracterizados por possuírem grande número de vacas nos plantéis. -/- -/- 2.1 Como saber que uma vaca está em cio/estro? -/- -/- O comportamento estral é causado por um aumento no estradiol sérico produzido pelo folículo ovulatório. O aumento do estradiol provoca mudanças de comportamento e modificações na genitália externa e interna. A vaca mostra-se inquieta, sua vocalização aumenta, ela anda mais, tenta montar em outras vacas e aceita montar no touro ou em outra vaca, bem como urinam com mais frequência (micção frequente). A vulva fica levemente inflamada, à palpação retal o útero pode ser visto com tônus ou turgor (duro e contraído) e ao massagear o colo do útero observa-se que sai abundante muco cristalino da vulva. O mecanismo clássico proposto na regulação do estro é baseado principalmente no papel do estradiol; no entanto, estudos recentes indicam que o GnRH pode participar da regulação do estro ao nível do hipotálamo. O estro possui duração entre 8 e 18 horas e a intensidade do mesmo é afetada por fatores ambientais e intrínsecos a vaca moderna (figuras de 1 a 6). -/- -/- -/- Figura 2: A observação do grupo sexualmente ativo facilita a identificação das vacas em estro. -/- Figura 1: As vacas em estro formam grupos ativos (grupo sexualmente ativo) separados do resto das vacas. A conformação desses grupos facilita a observação do estro. -/- -/- A formação de grupos de vacas é um fator ideal para a detecção de vacas em cio, elas ficam juntas e começam a montar uma nas outras, a cheirar a urina de ambas etc. comportamentos que podem ser visualizados de longe pelo tratador e diagnosticado o cio o mais breve possível para o manejo reprodutivo adotado pela propriedade seja para monta natural ou controlada e/ou inseminações artificiais (IA) e artificiais em tempo fixo (IATF). -/- -/- Figura 3: O único comportamento positivo do estro é a aceitação da monta de outra vaca. É frequente que a vaca que realiza a monta também esteja em estro, o que só será afirmado até que ela aceite a monta de outra vaca. -/- -/- Figura 4: Cada monta dura de 5 a 7 segundos -/- Figura 5: A vaca leiteira aceita de 5 a 30 montas distribuídas entre 8 e 18 horas. -/- Figura 6: Além das mudanças comportamentais, os estrogênios causam alterações na genitália interna. Uma delas é a produção de muco cervical, que juntamente com o turgor uterino, constituem os sinais genitais do estro. -/- -/- O cio pode ser dividido em três fases, a inicial, a fase de cio verdadeiro e a fase final. O cio verdadeiro quando é observado, é caracterizado pelo momento em que a vaca aceita claramente a monta. Por sua vez, os sinais de início e final de cio se misturam, apresentam nervosismo e inquietação, cheiram e lambem a vagina e a urina de outras vacas, apoiam a cabeça na garupa de outras fêmeas etc. (figura 7). Uma das sugestões adotadas nas propriedades para facilitar a identificação do cio em um rebanho é realizada pelos funcionários com a utilização de um bastão ou fita de coloração da garupa das vacas. -/- Figura 7: Principais sinais que demonstram que a vaca está entrando em cio. As imagens mostram o início do cio, cio verdadeiro e final do cio. -/- CONTINUA. BAIXE O PDF!!! -/- RESUMO -/- -/- < >Nos Estados Unidos, 300 milhões de dólares são perdidos devido à baixa eficiência na detecção do estro. A eficiência na detecção do estro no Brasil é de 40 a 50%. A meta de eficiência para detecção de estro é > 60%. Com a observação das vacas em dois períodos diários de três horas cada (manhã e tarde), consegue-se uma eficiência na detecção de estro de 80%. Menos de 20 por cento das vacas devem ter um intervalo de serviço duplo e nenhum de mais de 48 dias. A taxa de prenhez é obtida multiplicando-se a eficiência na detecção do estro pela porcentagem de concepção e dividindo por 100 (50 * 30/100 = 15%). A taxa de prenhez em rebanhos norte-americanos é de 15%. Nos Estados Unidos, para cada ponto percentual que diminui a taxa de prenhez, não há mais de US$ 12 a US$ 15 por vaca por ano. No Brasil, para cada ponto percentual que aumenta a taxa de prenhez, na faixa de 15 a 20%, é gerada uma renda anual adicional de $ 190 reais por vaca. Não mais que 25% das vacas devem estar vazias no 150º dia pós-parto. Não mais do que 8% devem as vacas ser cobertas no 250º dia pós-parto. 8% das vacas devem engravidar a cada mês. O estro ocorre 48 a 120 horas após o tratamento com PGF2α. 80% é a precisão na palpação do corpo lúteo. Quatorze dias devem decorrer entre duas injeções de PGF2α. Menos de 25% das vacas incluídas no programa de pré-sincronização devem chegar à IATF. No momento da ovulação, a primeira injeção de GnRH deve ser aplicada entre o quinto e o nono dia do ciclo estral. A inseminação cronometrada é realizada 14-16 horas após a segunda injeção de GnRH. O tratamento com dispositivos intravaginais liberadores de progesterona dura 12 dias. Se a duração do tratamento é menor deve-se injetar PGF2α ao retirá-lo. -/- -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- -/- ATUESTA, Jorge; DIAZA, Angela Gonella. Control hormonal del ciclo estral en bovinos y ovinos. Spei Domus, v. 7, n. 14, 2011. -/- COLAZO, Marcos Germán; MAPLETOFT, Reben. Fisiología del ciclo estral bovino. Ciencia Veterinaria, v. 16, n. 2, p. 31-46, 2017. -/- Fisiologia Clínica do Ciclo Estral de Vacas Leiteiras: Desenvolvimento Folicular, Corpo Lúteo e Etapas do Estro. Belo Jardim: IFPE, 2020. -/- Fisiologia da Reprodução Animal: Ovulação, Controle e Sincronização do Cio. Belo Jardim: IFPE, 2020. -/- DOBSON, H. et al. The high‐producing dairy cow and its reproductive performance. Reproduction in domestic animals, v. 42, p. 17-23, 2007. -/- DO VALLE, Ezequlel Rodrigues. O ciclo estral de bovinos e métodos de controle. EMBRAPA-CNPGC., 1991. -/- FURTADO, Diego Augusto et al. Inseminação artificial em tempo fixo em bovinos de corte. Revista científica eletrônica de medicina veterinária, v. 16, p. 1-25, 2011. -/- GALON, Nadav. The use of pedometry for estrus detection in dairy cows in Israel. Journal of Reproduction and Development, v. 56, n. S, p. S48-S52, 2010. -/- HOPPER, Richard M. (Ed.). Bovine reproduction. John Wiley & Sons, 2014. -/- LOPEZ, H.; SATTER, L. D.; WILTBANK, M. C. Relationship between level of milk production and estrous behavior of lactating dairy cows. Animal reproduction science, v. 81, n. 3-4, p. 209-223, 2004. -/- MACMILLAN, Keith L. Recent advances in the synchronization of estrus and ovulation in dairy cows. Journal of Reproduction and development, v. 56, n. S, p. S42-S47, 2010. -/- MUNIS DE OLIVEIRA, G. Fisiologia da Reprodução Bovina e Métodos de Controle do Ciclo Estral. Trabalho de conclusão do curso de especialização em Reprodução e Produção de Bovinos–UCB. Rio de Janeiro, Brasil, 2006. -/- O'CONNOR, MICHAEL L. Estrus detection. In: Current therapy in large animal theriogenology. WB Saunders, 2007. p. 270-278. -/- RIPPE, Christian A. El ciclo estral. In: Dairy Cattle Reproduction Conference. 2009. p. 111-116. -/- ROELOFS, Judith et al. When is a cow in estrus? Clinical and practical aspects. Theriogenology, v. 74, n. 3, p. 327-344, 2010. -/- VIVEIROS, Ana Tereza de Mendonça. Fisiologia da reprodução de bovinos. Lavras: UFLA, p. 62, 1997. (shrink)

This paper describes an AFOSR-supported basic research program that focuses on developing a new framework for combining hard with soft data in order to improve space situational awareness. The goal is to provide, in an automatic and near real-time fashion, a ranking of possible threats to blue assets (assets trying to be protected) from red assets (assets with hostile intentions). The approach is based on Conceptual Spaces models, which combine features from traditional associative and symbolic cognitive models. While Conceptual Spaces (...) are revolutionary, they lack an underlying mathematical framework. Several such frameworks have attempted to represent Conceptual Spaces, but by far the most robust is the model developed by Holender. His model utilizes integer linear programming in order to obtain an overall similarity value between observations and concepts that support the formation of hypotheses. This paper will describe a method for building Conceptual Spaces models for threats that utilizes ontologies as a means to provide a clear semantic foundation for this inferencing process; in particular threat ontologies and space domain ontologies are developed and employed in this approach. A space situational awareness use-case is presented involving a kinetic kill scenario and results are shown to assess the performance of this fusion-based inferencing framework. (shrink)

There is considerable disagreement about the epistemic value of novel predictive success, i.e. when a scientist predicts an unexpected phenomenon, experiments are conducted, and the prediction proves to be accurate. We survey the field on this question, noting both fully articulated views such as weak and strong predictivism, and more nascent views, such as pluralist reasons for the instrumental value of prediction. By examining the various reasons offered for the value of prediction across a range of inferential contexts , we (...) can see that neither weak nor strong predictivism captures all of the reasons for valuing prediction available. A third path is presented, Pluralist Instrumental Predictivism; PIP for short. (shrink)

The overall goal of the approach developed in this paper is to estimate the likelihood of a given kinetic kill scenario between hostile spacebased adversaries using the mathematical framework of Complex Conceptual Spaces Single Observation. Conceptual spaces are a cognitive model that provide a method for systematically and automatically mimicking human decision making. For accurate decisions to be made, the fusion of both hard and soft data into a single decision framework is required. This presents several challenges to this data (...) fusion framework. The first is the challenge involved in handling multiple complex terminologies, which is addressed by drawing on a set of Space Domain Ontologies. Another challenge is the complex combinatorics involved when considering all possible feature combinations. This can be mitigated by using integer linear programming optimization that is outlined by the Complex Conceptual Spaces Single Observation mathematical model framework. A third challenge is the complicated physics that is involved in a spacecraft collision that must be addressed to obtain a better understanding of threat assessment. Overcoming these various challenges allows for a quantitative ranking for the potential of a kinetic kill collision across multiple spacecraft pairs. In addition to overcoming these challenges this paper will break down threat assessment into four domains and identify a ranking of threat both for each individual domain and for the four domains combined. Simulation results are shown to verify the developed concepts. (shrink)

The practice of Emergency Management in Michigan raises anew the question of whose knowledge matters to whom and for what reasons, against the background of what projects, challenges, and systemic imperatives. In this paper, I offer a historical overview of state intervention laws across the United States, focusing specifically on Michigan’s Emergency Manager laws. I draw on recent analyses of these laws to develop an account of a phenomenon that I call epistemic redlining, which, I suggest, is a form of (...) group-based credibility discounting not readily countenanced by existing, ‘culprit-based’ accounts of epistemic injustice. I argue that epistemic redlining plays a crucial role in ongoing projects of racialized subordination and dispossession in Michigan, and that such discounting tends to have structural causes that can be difficult to identify and uproot. Contrary to the general thrust of recent work on the topic, I argue that epistemic redlining ought to be understood as a form of epistemic injustice. (shrink)

The no-miracles argument and the pessimistic induction are arguably the main considerations for and against scientific realism. Recently these arguments have been accused of embodying a familiar, seductive fallacy. In each case, we are tricked by a base rate fallacy, one much-discussed in the psychological literature. In this paper we consider this accusation and use it as an explanation for why the two most prominent `wholesale' arguments in the literature seem irresolvable. Framed probabilistically, we can see very clearly why realists (...) and anti-realists have been talking past one another. We then formulate a dilemma for advocates of either argument, answer potential objections to our criticism, discuss what remains (if anything) of these two major arguments, and then speculate about a future philosophy of science freed from these two arguments. In so doing, we connect the point about base rates to the wholesale/retail distinction; we believe it hints at an answer of how to distinguish profitable from unprofitable realism debates. In short, we offer a probabilistic analysis of the feeling of ennui afflicting contemporary philosophy of science. (shrink)

Lawrence Kohlberg's Approach to Moral Education presents what the late Lawrence Kohlberg regarded as the definitive statement of his educational theory. Addressing the sociology and social psychology of schooling, the authors propose that school culture become the center of moral education and research. They discuss how schools can develop as just and cohesive communities by involving students in democracy, and they focus on the moral decisions teachers and students face as they democratically resolve problems. As the authors put it: "...we (...) propose an educational renewal of our democratic society.... We have attempted to establish schools that do more than just teach about democratic citizenship, that are themselves democratic societies.". (shrink)

In this paper I engage interdisciplinary conversation on inaction as the dominant response to climate change, and develop an analysis of the specific phenomenon of complacency through a critical-feminist lens. I suggest that Chris Cuomo's discussion of the “insufficiency” problem and Susan Sherwin's call for a “public ethics” jointly point toward particularly promising harm-reduction strategies. I draw upon and extend their work by arguing that extant philosophical accounts of complacency are inadequate to the task of sorting out what it means (...) to be complacent on climate change. I offer a sketch for an alternative account, which I take to be a start in the direction of mapping out a diverse array of “motivational vices” that need to be named, grappled with, and remedied. (shrink)

When confronted with especially complex ecological and social problems such as climate change, how are we to think about responsibility for collective inaction? Social and political philosophers have begun to consider the complexities of acting collectively with a view to creating more just and sustainable societies. Some have recently turned their attention to the question of whether more or less formally organized groups can ever be held morally responsible for not acting collectively, or else for not organizing themselves into groups (...) capable of so doing. In this paper I argue that several questionable assumptions have shaped the character and scope of inquiry to this point, precluding us from grappling with a range of important questions concerning the epistemic dimensions of collective inaction. I offer an overview of recent conversation concerning collective inaction, advance a critique of the picture of responsibility that has emerged from this conversation, and propose an alternative approach to th... (shrink)

Volume 20, Issue 4, May 2020, Page 46-48.

Previous work has shown that the Complex Conceptual Spaces − Single Observation Mathematical framework is a useful tool for event characterization. This mathematical framework is developed on the basis of Conceptual Spaces and uses integer linear programming to find the needed similarity values. The work of this paper is focused primarily on space event characterization. In particular, the focus is on the ranking of threats for malicious space events such as a kinetic kill. To make the Conceptual Spaces framework work, (...) the similarity values between the contents of observations on the one hand and the properties of the entities observed on the other needs to be found. This paper shows how to exploit Dempster-Shafer theory to implement a statistical approach for finding these similarities values. This approach will allow a user to identify the uncertainty involved in similarity value data, which can later be propagated through the developed mathematical model in order for the user to know the overall uncertainty in the observation-to-concept mappings needed for space event characterization. (shrink)

One of the most frequently voiced criticisms of free will skepticism is that it is unable to adequately deal with criminal behavior and that the responses it would permit as justified are insufficient for acceptable social policy. This concern is fueled by two factors. The first is that one of the most prominent justifications for punishing criminals, retributivism, is incompatible with free will skepticism. The second concern is that alternative justifications that are not ruled out by the skeptical view per (...) se face significant independent moral objections. Yet despite these concerns, I maintain that free will skepticism leaves intact other ways to respond to criminal behavior—in particular preventive detention, rehabilitation, and alteration of relevant social conditions—and that these methods are both morally justifiable and sufficient for good social policy. The position I defend is similar to Derk Pereboom’s, taking as its starting point his quarantine analogy, but it sets out to develop the quarantine model within a broader justificatory framework drawn from public health ethics. The resulting model—which I call the public health -quarantine model—provides a framework for justifying quarantine and criminal sanctions that is more humane than retributivism and preferable to other non-retributive alternatives. It also provides a broader approach to criminal behavior than Pereboom’s quarantine analogy does on its own. (shrink)

When we ask what natural kinds are, there are two different things we might have in mind. The first, which I’ll call the taxonomy question, is what distinguishes a category which is a natural kind from an arbitrary class. The second, which I’ll call the ontology question, is what manner of stuff there is that realizes the category. Many philosophers have systematically conflated the two questions. The confusion is exhibited both by essentialists and by philosophers who pose their accounts in (...) terms of similarity. It also leads to misreading philosophers who do make the distinction. Distinguishing the questions allows for a more subtle understanding of both natural kinds and their underlying metaphysics. (shrink)

In this chapter I offer a critique of the received way of thinking about responsibility for collective inaction and propose an alternative approach that takes as its point of departure the epistemic agency exhibited by people navigating impossible situations together. One such situation is becoming increasingly common in the context of climate change: so-called “natural” disasters wreaking havoc on communities—flooding homes, collapsing infrastructures, and straining the capacities of existing organizations to safeguard lives and livelihoods. What happens when philosophical reflection begins (...) here—in places where the institutions and practices that have emerged over the last century seem incapable of addressing the problems communities face now, and where people find themselves turning to one another for the sake of their own survival? (shrink)

The accepted narrative treats John Stuart Mill’s Kinds as the historical prototype for our natural kinds, but Mill actually employs two separate notions: Kinds and natural groups. Considering these, along with the accounts of Mill’s nineteenth-century interlocutors, forces us to recognize two distinct questions. First, what marks a natural kind as worthy of inclusion in taxonomy? Second, what exists in the world that makes a category meet that criterion? Mill’s two notions offer separate answers to the two questions: natural groups (...) for taxonomy and Kinds for ontology. This distinction is ignored in many contemporary debates about natural kinds and is obscured by the standard narrative that treats our natural kinds just as a development of Mill’s Kinds. (shrink)

Material traces of the past are notoriously inscrutable; they rarely speak with one voice, and what they say is never unmediated. They stand as evidence only given a rich scaffolding of interpretation which is, itself, always open to challenge and revision. And yet archaeological evidence has dramatically expanded what we know of the cultural past, sometimes demonstrating a striking capacity to disrupt settled assumptions. The questions we address in Evidential Reasoning are: How are these successes realized? What gives us confidence (...) in the credibility and robustness, the trustworthiness, of the evidential claims based on archaeological data? And, what constitute best practices in building evidential claims, critically scrutinizing them and putting them to work in archaeological contexts? Rather than retreat to abstractions about how how science operates in the ideal, we approach this question by interrogating a number of close-to-the-ground case studies with the aim of teasing out the wisdom embodied in archaeological practice. The cases we consider – of fieldwork, strategies for working with old evidence, and the role of external resources – illuminate the role of various types of inferential scaffolding and bring into focus practice-grounded epistemic norms that we believe serve archaeologists better than the all-or-nothing ideals of truth and objectivity that dominate programmatic debate. (shrink)

There are two primary arguments against scientific realism, one pertaining to underdetermination, the other to the history of science. While these arguments are usually treated as altogether distinct, P. Kyle Stanford's ‘problem of unconceived alternatives’ constitutes one kind of synthesis: I propose that Stanford's argument is best understood as a broad modus ponens underdetermination argument, into which he has inserted a unique variant of the historical pessimistic induction. After articulating three criticisms against Stanford's argument and the evidence that he offers, (...) I contend that, as it stands, Stanford's argument poses no threat to contemporary scientific realism. Nonetheless, upon identifying two useful insights present in Stanford's general strategy, I offer an alternative variant of the modus ponens underdetermination argument, one that, although historically informed by science, requires no inductive premises. I contend that this non-inductive but historically informed variant of the modus ponens clarifies and considerably strengthens the case against scientific realism. (shrink)

The current economic/political system, neoliberalism, has touched every aspect of life globally. The doctrine of neoliberalism consists of three central propositions, that the market is real and part of the natural universal law; that unlimited economic growth is both possible and even desirable; and that human nature is coincident with market values and based solely on self-interest. All three of these propositions are seriously flawed and have caused immense human suffering and staggering environmental destruction. This paper is a reminder of (...) the failures of neoliberal policy and an appeal for change to a new institutional arrangement in which development trumps economic growth. This position is in contrast to Francis Fukuyama’s end-of-history thesis. He alleges there are no economic/political ideologies to compete with neoliberalism, the “TINA principle: There Is No Alternative”: the West has won. It is time to reintroduce Henry David Thoreau’s, and to a lesser extent, Adam Smith’s moral economies. Both have encourgaging insights, often overlooked by current academic economists, which could figure prominently in the conception of a new economy. (shrink)

The UK Government's Higher Education (Freedom of Speech) Bill is currently progressing through Parliament. The bill is designed to strengthen free speech and academic freedom in higher education, in response to what former Education Secretary Gavin Williamson describes as ‘the rise of intolerance and cancel culture upon our campuses’. But is there really a crisis of academic freedom in British universities?To see that there is, say Judith Suissa and Alice Sullivan, we need only look at the contemporary reality of (...) suppression of debate on sex and gender. The evidence they catalogue of suppression of research, of blacklisting, harassment and smear campaigns, of no-platforming, disinvitations and shutting down of events, is incontrovertible. The recent experience of scholars and students wishing to discuss the material reality and political salience of sex makes complacency about academic freedom a luxury we cannot afford.Suissa and Sullivan set out a powerful argument for the role of academic freedom in pursuing truth within the academy and developing democracy beyond it. They effectively counter attempts to narrow the scope of academic freedom so as to render it compatible with no-platforming. And they lay out a series of practical steps administrators can take to ensure that universities are places where an expansive and pluralistic intellectual climate prevails.This is a timely and compelling intervention in a vexed but urgent public debate. For their clear-sighted diagnosis of where and how academic freedom has been eroded in our universities, and for their judicious account of what must be done to rebuild it, Suissa and Sullivan deserve a wide and attentive hearing. (shrink)

Philip Kitcher develops the Galilean Strategy to defend realism against its many opponents. I explore the structure of the Galilean Strategy and consider it specifically as an instrument against constructive empiricism. Kitcher claims that the Galilean Strategy underwrites an inference from success to truth. We should resist that conclusion, I argue, but the Galilean Strategy should lead us by other routes to believe in many things about which the empiricist would rather remain agnostic. 1 Target: empiricism 2 The Galilean Strategy (...) 3 Strengthening the argument 4 Success and truth 5 Conclusion. (shrink)

Not only did Paracelsus (1493-1541) censure the logic of the Aristotelians, but also their "Godless" approach to questioning nature. He declared that Aristotle was “a heathen whose work had rightly been condemned repeatedly in church councils." In this essay I elucidate some of the more salient features of Paracelsus’s "epistemology," and draw parallels between his notion of experientia (Erfahrung) and that of Hans-Georg Gadamer. I also discuss Paracelsus’s educational metaphor, his creation myth, and the mysterious doctrine of signatures en route (...) to uncovering his peculiar understanding of the relationship between theory, practice, and experience. (shrink)

Heidegger's interpretation of Nietzsche has been canonized in the philosophical tradition as an almost perfect demonstration of how the forgetfulness of Being continues the dominant positions of modern metaphysics. However, the role of reading in the interpretative process casts a different light on Heidegger's approach to Nietzsche and his relationship to the philosophical tradition. This paper is concerned with three aspects of Heidegger's work, namely, (i) the role of Kant and Schopenhauer in Nietzsche's critique of metaphysics; (ii) Nietzsche's 'inversion' of (...) Platonism; and (iii) Heidegger's contribution to a hermeneutical reappraisal of Nietzsche's thought. (shrink)

This paper, written in Romanian, compares fictionalism, nominalism, and neo-Meinongianism as responses to the problem of objectivity in mathematics, and then motivates a fictionalist view of objectivity as invariance.

My commentary deals with the fourth chapter of Against Purity, entitled “Consuming Suffering,” where Shotwell invites us to imagine what an alternative to ethical individualism might look like in practice. I am particularly interested in the analogy she develops to help pull us into the frame of what she calls a “distributed” or “social” approach to ethics. I will argue that grappling with this analogy can help illuminate three challenges confronting those of us seeking a genuine alternative to ethical individualism: (...) first, that of recognizing that and how certain organizational forms work to entrench an individualistic orientation to the world; second, that of acknowledging the inadequacy of alternatives to individualism that are merely formal in character; and third, that of avoiding the creation of organizational forms that foster purism at the collective level. (shrink)

Virtues, broadly understood as stable and robust dispositions for certain responses across morally relevant situations, have been a growing topic of interest in psychology. A central topic of discussion has been whether studies showing that situations can strongly influence our responses provide evidence against the existence of virtues (as a kind of stable and robust disposition). In this review, we examine reasons for thinking that the prevailing methods for examining situational influences are limited in their ability to test dispositional stability (...) and robustness; or, then, whether virtues exist. We make the case that these limitations can be addressed by aggregating repeated, cross-situational assessments of environmental, psychological and physiological variables within everyday life—a form of assessment often called ecological momentary assessment (EMA, or experience sampling). We, then, examine how advances in smartphone application (app) technology, and their mass adoption, make these mobile devices an unprecedented vehicle for EMA and, thus, the psychological study of virtue. We, additionally, examine how smartphones might be used for virtue development by promoting changes in thought and behavior within daily life; a technique often called ecological momentary intervention (EMI). While EMA/I have become widely employed since the 1980s for the purposes of understanding and promoting change amongst clinical populations, few EMA/I studies have been devoted to understanding or promoting virtues within non-clinical populations. Further, most EMA/I studies have relied on journaling, PDAs, phone calls and/or text messaging systems. We explore how smartphone app technology provides a means of making EMA a more robust psychological method, EMI a more robust way of promoting positive change, and, as a result, opens up new possibilities for studying and promoting virtues. (shrink)

Philosophical arguments regarding academic freedom can sometimes appear removed from the real conflicts playing out in contemporary universities. This paper focusses on a set of issues at the front line of these conflicts, namely, questions regarding sex, gender and gender identity. We document the ways in which the work of academics has been affected by political activism around these questions and, drawing on our respective disciplinary expertise as a sociologist and a philosopher, elucidate the costs of curtailing discussion on fundamental (...) demographic and conceptual categories. We discuss some philosophical work that addresses the conceptual distinction between academic freedom and free speech and explore how these notions are intertwined in significant ways in universities. Our discussion elucidates and emphasises the educational costs of curtailing academic freedom. (shrink)

Philosophical treatments of natural kinds are embedded in two distinct projects. I call these the philosophy of science approach and the philosophy of language approach. Each is characterized by its own set of philosophical questions, concerns, and assumptions. The kinds studied in the philosophy of science approach are projectible categories that can ground inductive inferences and scientific explanation. The kinds studied in the philosophy of language approach are the referential objects of a special linguistic category—natural kind terms—thought to refer directly. (...) Philosophers may hope for a unified account addresses both sets of concerns. This paper argues that this cannot be done successfully. No single account can satisfy both the semantic objectives of the philosophy of language approach and the explanatory projects of the philosophy of science approach. After analyzing where the tensions arise, I make recommendations about assumptions and projects that are best abandoned, those that should be retained, and those that should go their separate ways. I also recommend adopting the disambiguating terminology of “scientific kinds” and “natural kinds” for the different notions of kinds developed in these different approaches. (shrink)

Spinoza's use of the phrase “sui iuris” in the Tractatus Politicus gives rise to the following paradox. On the one hand, one is said to be sui iuris to the extent that one is rational; and to the extent that one is rational, one will steadfastly obey the laws of the state. However, Spinoza also states that to the extent that one adheres to the laws of the state, one is not sui iuris, but rather stands under the power [sub (...) potestate] of the state (TP 3/5). It seems, then, that to the extent that one is sui iuris, one will not, in fact, be sui iuris. In this paper, I offer an interpretation of Spinoza's notion of being sui iuris that enables us to overcome this paradox and sheds light on Spinoza's relationship to the republican tradition. I work towards this goal by distinguishing between two ways in which Spinoza uses the locution, which correspond to two different conceptions of power: potentia and potestas. This distinction not only allows us to save Spinoza from internal inconsistency, it also enables us to see one important way in which Spinoza stands outside of the republican tradition, since he conceives of liberty not as constituted by independence, or citizenship in a res publica, but as being sui iuris in the first sense described above: being powerful. (shrink)

It has been common wisdom for centuries that scientific inference cannot be deductive; if it is inference at all, it must be a distinctive kind of inductive inference. According to demonstrative theories of induction, however, important scientific inferences are not inductive in the sense of requiring ampliative inference rules at all. Rather, they are deductive inferences with sufficiently strong premises. General considerations about inferences suffice to show that there is no difference in justification between an inference construed demonstratively or ampliatively. (...) The inductive risk may be shouldered by premises or rules, but it cannot be shirked. Demonstrative theories of induction might, nevertheless, better describe scientific practice. And there may be good methodological reasons for constructing our inferences one way rather than the other. By exploring the limits of these possible advantages, I argue that scientific inference is neither of essence deductive nor of essence inductive. (shrink)

This paper provides a method for characterizing space events using the framework of conceptual spaces. We focus specifically on estimating and ranking the likelihood of collisions between space objects. The objective is to design an approach for anticipatory decision support for space operators who can take preventive actions on the basis of assessments of relative risk. To make this possible our approach draws on the fusion of both hard and soft data within a single decision support framework. Contextual data is (...) also taken into account, for example data about space weather effects, by drawing on the Space Domain Ontologies, a large system of ontologies designed to support all aspects of space situational awareness. The framework is coupled with a mathematical programming scheme that frames a mathematically optimal approach for decision support, providing a quantitative basis for ranking potential for collision across multiple satellite pairs. The goal is to provide the broadest possible information foundation for critical assessments of collision likelihood. (shrink)

Philosophy has a language problem. A recent study by Schwitzgebel, Huang, Higgins and Gonzalez-Cabrera (2018) found that, in a sample of papers published in elite journals, 97% of citations were to work originally written in English. 73% of this same sample didn’t cite any paper that had been originally written in a language other than English. Finally, a staggering 96% of elite journal editorial boards are primarily affiliated with an Anglophone university. This is consistent with earlier data suggesting that journal (...) submissions from countries that are outside the Anglophone world and Europe have disturbingly low chances of being accepted. The route forward is not entirely clear. What is clear, however, is that this structural disadvantage deserves closer philosophical and empirical attention. We owe this to current and future members of our philosophical community who speak English non-natively. We also need this if we want to make sure philosophy is enriched by a diverse group of thinkers who have a grasp of different languages, and of the cultures strongly associated with them. (shrink)

In Nicomachean Ethics X.7–8, Aristotle defends a striking view about the good for human beings. According to Aristotle, the single happiest way of life is organized around philosophical contemplation. According to the narrowness worry, however, Aristotle's contemplative ideal is unduly Procrustean, restrictive, inflexible, and oblivious of human diversity. In this paper, I argue that Aristotle has resources for responding to the narrowness worry, and that his contemplative ideal can take due account of human diversity.